The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]
Human,Mouse,Rat
WB,IHC-P,IHC-F,IF,IP,Flow-Cyt
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.